22 research outputs found

    Analysis of quantum coherence for localized fermionic systems in an accelerated motion

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    Although quantum coherence is a well known phenomenon in quantum information theory and quantum optics, it has been investigated from the resource theory perspective only recently. Furthermore, quantum coherence has important implications in relativistic quantum information where the degradation of entanglement can be attributed to decoherence. In this paper, we investigate the quantum coherence of Dirac field modes localized in a cavity as observed by two relatively accelerated observers. The acceleration is assigned very small values and its effects are investigated in a perturbative regime. For this purpose, we use parameterized two-qubit pure entangled state and a Werner state. We find that coherence shows a periodic degradation due to accelerated motion. However, this degradation can be balanced by adjusting the durations of uniform and accelerated motion. Moreover, it is found that dynamics of quantum coherence closely resembles that of entanglement under the same settings. This similarity confirms the recent attempts to relate the resource theories of coherence and entanglement in a relativistic regime.publishedVersionUnit Licence Agreemen

    Multiscale Hybrid Nonlocal Means Filtering Using Modified Similarity Measure

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    A new multiscale implementation of nonlocal means filtering (MHNLM) for image denoising is proposed. The proposed algorithm also introduces a modification of the similarity measure for patch comparison. Assuming the patch as an oriented surface, the notion of a normal vectors patch is introduced. The inner product of these normal vectors patches is defined and then used in the weighted Euclidean distance of intensity patches as the weight factor. The algorithm involves two steps: the first step is a multiscale implementation of an accelerated nonlocal means filtering in the discrete stationary wavelet domain to obtain a refined version of the noisy patches for later comparison. The next step is to apply the proposed modification of standard nonlocal means filtering to the noisy image using the reference patches obtained in the first step. These refined patches contain less noise, and consequently the computation of normal vectors and partial derivatives is more precise. Experimental results show equivalent or better performance of the proposed algorithm compared to various state-of-the-art algorithms

    Unsteady MHD Bionanofluid Flow in a Porous Medium with Thermal Radiation near a Stretching/Shrinking Sheet

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    This research aims at providing the theoretical effects of the unsteady MHD stagnation point flow of heat and mass transfer across a stretching and shrinking surface in a porous medium including internal heat generation/absorption, thermal radiation, and chemical reaction. The fundamental principles of the similarity transformations are applied to the governing partial differential equations (PDEs) that lead to ordinary differential equations (ODEs). The transformed ODEs are numerically solved by the shooting algorithm implemented in MATLAB, and verification is done from MATLAB built-in solver bvp4c. The numerical data produced for the skin friction coefficient, the local Nusselt number, and the local Sherwood number are compared with the available result and found to be in a close agreement. The impact of involved physical parameters on velocity, temperature, concentration, and density of motile microorganisms profiles is scrutinized through graphs. It is analyzed that the skin friction coefficient enhances with increasing values of an unsteady parameter A, magnetic parameter M, and porosity parameter Kp. In addition, we observe that the density of a motile microorganisms profile enhances larger values of the bioconvection Lewis number Lb and Peclet number Pe and decreases with the increasing values of an unsteady parameter A.publishedVersio

    Hybrid Deep Learning Framework for Reduction of Mixed Noise via Low Rank Noise Estimation

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    In this paper, an innovative hybridized deep learning framework (EN-CNN) is presented for image noise reduction where the noise originates from heterogeneous sources. More specifically, EN-CNN is applied to the benchmark natural images affected by a mixture of additive white gaussian noise (AWGN) and impulsive noise (IN). Reduction of mixed noise (AWGN and IN) is relatively more involved as compared to removing simply one type of noise. In fact, mitigating the impact of a mixture of multiple noise types becomes exceedingly challenging due to simultaneous presence of different noise statistics. Although, various effective deep learning approaches and the classical state-of-the-art approaches like WNNM have been used to suppress AWGN noise only, the same techniques are not suitable in case of mixed noise. In this context, EN-CNN can not only infer changed noise statistics but can also effectively eliminate residual noise. Firstly, EN-CNN employs the classical method of neighborhood filtering followed by non-local low rank estimation to respectively reduce IN noise and estimate the residual noise characteristics after reducing IN noise. As a result of this step, we obtain a pre-processed image with residual noise statistics. Secondly, convolutional neural network (CNN) is applied to the pre-processed image based on the noise statistics inferred in the first step. This two pronged strategy, in conjunction with the deep learning mechanism, effectively handles the mixed noise suppression. As a result, the suggested framework yields promising results as compared to various state-of-the-art approaches.publishedVersio

    Twelve-month observational study of children with cancer in 41 countries during the COVID-19 pandemic

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    Introduction Childhood cancer is a leading cause of death. It is unclear whether the COVID-19 pandemic has impacted childhood cancer mortality. In this study, we aimed to establish all-cause mortality rates for childhood cancers during the COVID-19 pandemic and determine the factors associated with mortality. Methods Prospective cohort study in 109 institutions in 41 countries. Inclusion criteria: children <18 years who were newly diagnosed with or undergoing active treatment for acute lymphoblastic leukaemia, non-Hodgkin's lymphoma, Hodgkin lymphoma, retinoblastoma, Wilms tumour, glioma, osteosarcoma, Ewing sarcoma, rhabdomyosarcoma, medulloblastoma and neuroblastoma. Of 2327 cases, 2118 patients were included in the study. The primary outcome measure was all-cause mortality at 30 days, 90 days and 12 months. Results All-cause mortality was 3.4% (n=71/2084) at 30-day follow-up, 5.7% (n=113/1969) at 90-day follow-up and 13.0% (n=206/1581) at 12-month follow-up. The median time from diagnosis to multidisciplinary team (MDT) plan was longest in low-income countries (7 days, IQR 3-11). Multivariable analysis revealed several factors associated with 12-month mortality, including low-income (OR 6.99 (95% CI 2.49 to 19.68); p<0.001), lower middle income (OR 3.32 (95% CI 1.96 to 5.61); p<0.001) and upper middle income (OR 3.49 (95% CI 2.02 to 6.03); p<0.001) country status and chemotherapy (OR 0.55 (95% CI 0.36 to 0.86); p=0.008) and immunotherapy (OR 0.27 (95% CI 0.08 to 0.91); p=0.035) within 30 days from MDT plan. Multivariable analysis revealed laboratory-confirmed SARS-CoV-2 infection (OR 5.33 (95% CI 1.19 to 23.84); p=0.029) was associated with 30-day mortality. Conclusions Children with cancer are more likely to die within 30 days if infected with SARS-CoV-2. However, timely treatment reduced odds of death. This report provides crucial information to balance the benefits of providing anticancer therapy against the risks of SARS-CoV-2 infection in children with cancer

    Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019

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    Background: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10–24 years during the past three decades. Methods: Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolute numbers and age-standardised rates per 100 000 population by sex, age group (10–14, 15–19, and 20–24 years), and sociodemographic index (SDI) with 95% uncertainty intervals (UIs). We report percentage changes in deaths and DALYs between 1990 and 2019. Findings: In 2019, 369 061 deaths (of which 214 337 [58%] were transport related) and 31·1 million DALYs (of which 16·2 million [52%] were transport related) among adolescents aged 10–24 years were caused by transport and unintentional injuries combined. If compared with other causes, transport and unintentional injuries combined accounted for 25% of deaths and 14% of DALYs in 2019, and showed little improvement from 1990 when such injuries accounted for 26% of adolescent deaths and 17% of adolescent DALYs. Throughout adolescence, transport and unintentional injury fatality rates increased by age group. The unintentional injury burden was higher among males than females for all injury types, except for injuries related to fire, heat, and hot substances, or to adverse effects of medical treatment. From 1990 to 2019, global mortality rates declined by 34·4% (from 17·5 to 11·5 per 100 000) for transport injuries, and by 47·7% (from 15·9 to 8·3 per 100 000) for unintentional injuries. However, in low-SDI nations the absolute number of deaths increased (by 80·5% to 42 774 for transport injuries and by 39·4% to 31 961 for unintentional injuries). In the high-SDI quintile in 2010–19, the rate per 100 000 of transport injury DALYs was reduced by 16·7%, from 838 in 2010 to 699 in 2019. This was a substantially slower pace of reduction compared with the 48·5% reduction between 1990 and 2010, from 1626 per 100 000 in 1990 to 838 per 100 000 in 2010. Between 2010 and 2019, the rate of unintentional injury DALYs per 100 000 also remained largely unchanged in high-SDI countries (555 in 2010 vs 554 in 2019; 0·2% reduction). The number and rate of adolescent deaths and DALYs owing to environmental heat and cold exposure increased for the high-SDI quintile during 2010–19. Interpretation: As other causes of mortality are addressed, inadequate progress in reducing transport and unintentional injury mortality as a proportion of adolescent deaths becomes apparent. The relative shift in the burden of injury from high-SDI countries to low and low–middle-SDI countries necessitates focused action, including global donor, government, and industry investment in injury prevention. The persisting burden of DALYs related to transport and unintentional injuries indicates a need to prioritise innovative measures for the primary prevention of adolescent injury. Funding: Bill & Melinda Gates Foundation

    Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

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    Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings: Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990–2010 time period, with the greatest annualised rate of decline occurring in the 0–9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10–24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10–24 years were also in the top ten in the 25–49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50–74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation: As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and developm nt investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens
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